If you have a computer with an XE compatible RAM upgrade with ANTIC banking, you could do this, and reduce the footprint in main memory. However, you then run risk of interfering with DOSes that may want to use the RAM. There's no kernal-level memory management inherent in the Atari OS.
If you are running SDX, there is a memory manager you can call, however, while I believe you can reserve a full bank via SDX, you cant specify that it be an ANTIC-bankable bank. And you're then locked in to SDX for your program. (And besides, SDX already has its own 64 and 80 column drivers)